Factors Influencing Good Response of Methotrexate Treatment in Rheumatoid Arthritis Patients

  • Fara Fauzia Post graduate program, Department of Epidemiology, Faculty of Public Health, Universitas Indonesia
  • Nurhayati Adnan Prihartono Post graduate program, Department of Epidemiology, Faculty of Public Health, Universitas Indonesia
  • Rudy Hidayat Division of Rheumatology, Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia /Cipto Mangunkusumo Hospital
Keywords: Rheumatoid Arthritis, Methotrexate, Therapy

Abstract

Rheumatoid arthritis (RA) is a systemic and chronic autoimmune disease with joint manifestations. Delays in RA treatment will pose a risk of permanent joint damage and increased mortality risk. Diagnosis as early as possible, followed by appropriate therapy, will prevent various complications due to RA, aiming to achieve a condition of remission or minimal low disease activity. The treatment choice for RA is currently a group of disease-modifying anti-rheumatic drugs (DMARDs), with methotrexate (MTX) as the first choice. Various studies have reported various factors that play a role in the success of MTX treatment, including younger age, male sex, normal body mass index, not smoking, early treatment, number of joints involved, inflammatory factors (LED/CRP) and negative serological factors (RF/anti-CCP).

Downloads

Download data is not yet available.
Published
2023-02-04
How to Cite
Fauzia, F., Prihartono, N. A., & Hidayat, R. (2023). Factors Influencing Good Response of Methotrexate Treatment in Rheumatoid Arthritis Patients. Journal Of The Indonesian Medical Association, 72(6), 302 - 308. https://doi.org/10.47830/jinma-vol.72.6-2022-850