The Relevance of Right and Left Hemisphere Classification to Predict Cognitive Outcome After Stroke

  • Savira Butsainah Dienanta Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia
  • Muhammad Hamdan Department of Neurology, Soetomo General Hospital, Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia
  • Soetjipto Department of Psychiatry, Soetomo General Hospital, Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia
  • Abdulloh Machin Department of Neurology, Soetomo General Hospital, Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia
Keywords: cognitive impairment, MMSE, stroke

Abstract

Introduction: Stroke is the fifth leading cause of disability-adjusted life years (DALYs) in the world. Cognitive impairment is one of the disabilities found in the acute phase of stroke and persists in long-term outcomes which can be assessed using the Mini-Mental State Examination (MMSE). However, a clinical classification to predict the cognitive outcome remained unclear. This study is aimed to identify differences of MMSE results in stroke patients between right and left hemisphere lesions to ensure the mentioned location classifications may contribute to cognitive outcome prediction.
Method: With the cross-sectional analytic observational design, 32 acute phase patients hospitalized in the Neurology Department Soetomo General Hospital from October–December 2019 were assessed using the Indonesian version of MMSE with purposive sampling and analyzed using the chi-square test.
Result: There was no significant difference between MMSE scores in right or left hemisphere lesion. This might happen because (1) MMSE was insensitive and not a domain-specific test; (2) a more specific infarct location was needed to predict cognitive outcome post-stroke, including microarchitecture of the brain especially those involved in the cortico-striato-thalamocortical loop.
Conclusion: The right or left hemisphere lesion classification did not contribute significantly to predict cognitive impairment.

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Author Biographies

Savira Butsainah Dienanta, Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia

Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia

Muhammad Hamdan, Department of Neurology, Soetomo General Hospital, Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia

Department of Neurology, Soetomo General Hospital, Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia

Soetjipto, Department of Psychiatry, Soetomo General Hospital, Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia

Department of Psychiatry, Soetomo General Hospital, Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia

Abdulloh Machin, Department of Neurology, Soetomo General Hospital, Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia

Department of Neurology, Soetomo General Hospital, Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia

Published
2020-09-03
How to Cite
Dienanta, S., Hamdan, M., Soetjipto, S., & Machin, A. (2020). The Relevance of Right and Left Hemisphere Classification to Predict Cognitive Outcome After Stroke. Journal Of The Indonesian Medical Association, 70(8), 151-158. https://doi.org/10.47830/jinma-vol.70.8-2020-201