Relationship of Autonomic Dysfunction with The Severity of Parkinsonism Patients

  • Imelda Floransia Departemen Neurologi Fakultas Kedokteran Universitas Sam Ratulangi/RSUP Prof. Dr. R.D. Kandou Manado
  • Corry N. Mahama Departemen Neurologi Fakultas Kedokteran Universitas Sam Ratulangi/RSUP Prof. Dr. R.D. Kandou Manado
  • Herlyani Khosama Departemen Neurologi Fakultas Kedokteran Universitas Sam Ratulangi/RSUP Prof. Dr. R.D. Kandou Manado
Keywords: Autonomic Disfunction, Hoehn and Yahr, Parkinsonism, SCOPA-AUT

Abstract

Introduction: Autonomic dysfunction is one of the non-motor symptoms of parkinsonism but has not been of clinical concern. The purpose of this study was to assess the relationship of autonomic dysfunction with the severity of parkinsonism patients.
Method: A total of 121 outpatient subjects in the Neurology Clinic of Prof. Dr. R. D. Kandou Hospital Manado, sample selection is done consecutively in analytic cross-sectional studies. The patient characteristics, symptoms and examination of autonomic dysfunction are recorded. Data were analyzed using chi square, Mann Whitney U, Kruskal-Wallis and logistic regression.
Result: Almost all variables measuring autonomic function tended to show a higher degree of severity of parkinsonism (p <0.001). Each increase in the SCOPA-AUT INA score tends to increase the odds of the Hoehn and Yahr stage (OR> 1) also in the greater orthostatic blood pressure difference test, older age, longer illness, longer treatment period, and use of a combination of antiparkinson drugs.
Conclusion: Autonomic dysfunction is significantly related to the severity of parkinsonism.

Downloads

Download data is not yet available.
Published
2020-03-13
How to Cite
Imelda Floransia, Corry N. Mahama, & Herlyani Khosama. (2020). Relationship of Autonomic Dysfunction with The Severity of Parkinsonism Patients. Journal Of The Indonesian Medical Association, 69(12), 349-359. https://doi.org/10.47830/jinma-vol.69.12-2019-166