The Relationship Of Hypercoagulation And Mortality In Hospitalized Confirmed Patients Corona Virus Disease-19 (Covid-19)

Abstract

Introduction: The clinical manifestations of COVID-19 vary from asymptomatic to symptomatic. COVID-19 patients with severe symptoms often have coagulation disorders similar to systemic coagulopathy. This is associated with a significant increase in mortality. The purpose of this study was to determine the relationship between hypercoagulation and death in hospitalized patients with confirmed COVID-19.
Method: This research is an analytic observational, quantitative approach with a cross sectional research design. The method of collecting secondary data comes from medical record data on inpatients who have confirmed COVID-19 at the Islamic Hospital in Jakarta Sukapura, by total sampling.
Result: There are 625 research subjects. Most of the subjects were women (52.3%) at the age of 50-59 years (26.6%). The status of living patients was (98.9 %). The value of D dimer tends to increase, the value of PT is normal, and the value of APTT is normal. The Case Fatality Rate (CFR) in the subject was 0.0112% (CFR < 4.35% = low CFR).
Conclusion: There is a low CFR in hospitalized patients with confirmed COVID-19 at RSIJ Sukapura. The results of the examination on the parameters of coagulant agents based on patient status in hospitalized patients who were confirmed to be COVID-19 at RSIJ Sukapura, on the D-dimer and APTT parameters there was no significant relationship, while on the PT parameter there was a significant relationship.