Profil of Toxigenic Corynebacterium diphtheriae Isolate in East Java, 2012-2017

  • Sugi Deny Pranoto Soegianto Department of Child Health, Faculty of Medicine Universitas Airlangga/Dr. Soetomo General Hospital, Surabaya
  • Adi Pramono Hendrata Balai Besar Laboratorium Kesehatan Daerah (BBLK), Surabaya
  • Eveline Irawan Balai Besar Laboratorium Kesehatan Daerah (BBLK), Surabaya
  • Ismoedijanto Department of Child Health, Faculty of Medicine Universitas Airlangga/Dr. Soetomo General Hospital, Surabaya
  • Dominicus Husada Department of Child Health, Faculty of Medicine Universitas Airlangga/ Dr. Soetomo General Hospital, Surabaya
Keywords: Corynebacterium diphtheriae, Toxigenic, Profile, East java

Abstract

Introduction: Diphtheria has been reported as an outbreak in some regions inIndonesia, most of the cases are from East Java.Objective: To describe the profile of toxigenic Corynebacterium diphtheriaeisolates in East Java.

Methods. An descriptive study from August 20th -November 30th, 2018. Isolates was selected by cluster random sampling. The viability and toxigenicity testwere done in BBLK Surabaya. Viable and toxigenic isolates were done forcharacteristic analysis.

Result: A total of 114 isolates, 6 were non-viable, 108 were viable and toxi-genic. The majority of the hosts were male (58,3%), median age 6,5-year-old(minimum 1, maximum 14-year-old), 50% from the 1-5-year-old age group. Highest origin of isolates from patients (78,7%) rather than carriers (21,3%).The most isolates from Madura (47,2%) and horseshoe area (20,4%). Most ofthem (74.1%) were taken from a pharyngeal swab rather than a nasal swab(25,4%). Mitis was 76,9% and gravis was 23,1%.

Conclusion: In this study, the majority of toxigenic Corynebacterium diphtheriae were found in the 1-5-year-old age group and most of them domi-cile in Madura and horseshoe area. Most of the isolates were taken from apharyngeal swab of patients. Mitis was the major variant.

Downloads

Download data is not yet available.
Published
2019-10-02
How to Cite
Soegianto, S. D. P., Hendrata, A. P., Irawan, E., Ismoedijanto, & Husada, D. (2019). Profil of Toxigenic Corynebacterium diphtheriae Isolate in East Java, 2012-2017. Journal Of The Indonesian Medical Association, 69(2), 78-82. https://doi.org/10.47830/jinma-vol.69.2-2019-75
Viewer: 261 times
Download PDF downloaded: 371 times