Differences in Survival of Chronic Kidney Disease Patients Based on Initial Glomerular Filtration Rate (eGFR)

Abstract

Introduction: One of the leading causes of death in the world today is chronic kidney disease (CKD). In 2021, the death rate for CKD patients receiving hemodialysis rose by 0.6%. This study aims to determine the relationship between the initial Glomerular Filtration Rate (eGFR) value and the survival of stage V CKD patients undergoing regular hemodialysis.
Method: This cohort-retrospective analytical study was carried out at Prof. Dr. Chairuddin’s P. Lubis Hospital in Medan between July and September of 2024. Patients with stage V CKD who were registered in their medical records and began receiving regular hemodialysis in 2021–2023 met the inclusion criteria for the study sample, while patients with incomplete medical record data met the exclusion criteria. The Kaplan Meier survival curve and the log-rank test were used to evaluate the data.
Result: The age group of 45–59 years old (40%), males (64.6%), beginning hemodialysis with an initial eGFR value of less than 5.0 ml/minute/1.73 m2 (44.6%), and receiving regular hemodialysis for less than 12 months (56.9%) included the biggest distribution of the 65 research samples. The average initial eGFR value was 5.74 ml/minute/1.73 m2. The findings of the log-rank test were not significant (p greater than 0.05).
Conclusion: There is no significant difference in survival based on the initial eGFR value at the time of hemodialysis initiation.