Detection of Helicobacter pylori Antigen in GERD and Non-GERD Patient at Atma Jaya Hospital
Introduction: Helicobacter pylori (H. Pylori) is one of normal human microbiota live in human stomach and often associated with dyspepsia, however, its association with Gastroesophageal Reflux Disease (GERD) is still controversial. The diagnosis of H. pylori is often established through histopathological examination, an invasive urease tests, and urea breath test (UBT. Serological tests are also used to diagnose H. pylori, one of which is Stool Antigen Test (SAT), which is cheaper, non-invasive and easier to operate. The purpose of this study was to detect H. pylori antigen in GERD and non-GERD patients at Atma Jaya Hospital.
Method. This study was a descriptive cross-sectional. Participants in this study were adult patients hospitalised in Atma Jaya Hospital from August 2018 - November 2018, interviewed with GERDQ questionnaire and stool samples were collected. Stool Antigen Test was carried out using SAT from Biocare®.
Results. Thirty participants were included in this study, consisted of 22 women and 8 men, and predominated by adult age group (35–64 years old). Forty percent participants were GERD group consisted of 75% women. Positive SAT test results in the GERD group was 16.67%, non-GERD was 11.11%, and negative SAT test results in the GERD group was 91.67%, non-GERD was 77.78%.
Conclusion: The presence of H. pylori antigen was detected in women in the adult age group. It seemed the presence of H. pylori was not different from GERD group and non-GERD group.