Diagnostic Test of Neutrofil-Lymphocyte Ratio In Acute Appendicitis In Zainoel Abidin General Hospital Banda Aceh

  • Idham Adyasa Manggala Putra Surgery, Faculty of Medicine, Syiah Kuala University, Zainoel Abidin, General Hospital Banda Aceh
  • Dian Adi Syahputra Departement of Surgery, Faculty of Medicine, Syiah Kuala University, Zainoel Abidin, General Hospital Banda Aceh
  • Muhammad Yusuf Departement of Surgery, Faculty of Medicine, Syiah Kuala University, Zainoel Abidin, General Hospital Banda Aceh
  • Muntadhar Muhammad Isa Departement of Surgery, Faculty of Medicine, Syiah Kuala University, Zainoel Abidin, General Hospital Banda Aceh
  • Safrizal Rahman Departement of Surgery, Faculty of Medicine, Syiah Kuala University, Zainoel Abidin, General Hospital Banda Aceh
  • Jufriady Ismy Departement of Surgery, Faculty of Medicine, Syiah Kuala University, Zainoel Abidin, General Hospital Banda Aceh
Keywords: Acute appendicitis, Cut off point, Sensitivity, Specificity, Neutrophil- Lymphocyte Ratio.

Abstract

Introductions: Acute appendicitis is an inflammation that occurs in the Vermiformis appendix. Inflammatory response to acute appendicitis is characterized by the activation of cellular and molecular effectors, including recruitment and activation of neutrophils. The Neutrophil Lymphocytes Ratio (NLR) is a comparison of neutrophil counts with lymphocytes used as a simple benchmark.
Methods: we analysed with observational diagnostic test analytical design of retrospective cross sectional studies. The study subjects were acute appendicitis patients at Zainoel Abidin General Hospital in 2018-2019. Subjects upon arrival performed a blood test, and then calculated NLR, the result of NLR count compared to post-appendectomy anatomical pathology examination. The data is analyzed with descriptive statistical analysis, ROC curve analysis and diagnostic tests.
Results: There were 176 samples was came to emergency room with diagnosed appendicitis, the most age was 17-25 years (31.2%), 81 male (46%), 95 female (54%). From patological anatomy result were 129 acute appendicitis and 47 chronic appendicitis. From the AUC ROC 0.96 obtained cut off point NLR > 3,209 in acute appendicitis. Diagnostic tests obtained sensitivity 83,72% specificity 82,98%, positive guess value 97,71% and negative guess value 65,00% with 83,52% accuracy.
Conclusion: we concluded NLR may predict diagnosis of acute appendicitis with NLR > 3,209, sensitivity scores of 83,72% specificity 82,98%.

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Published
2021-09-21
How to Cite
Adyasa Manggala Putra, I., Syahputra, D. A., Yusuf, M., Isa, M. M., Rahman, S., & Ismy, J. (2021). Diagnostic Test of Neutrofil-Lymphocyte Ratio In Acute Appendicitis In Zainoel Abidin General Hospital Banda Aceh. Journal Of The Indonesian Medical Association, 71(4), 170 - 176. https://doi.org/10.47830/jinma-vol.71.4-2021-426